Kumasi is a cosmopolitan city with a good road network and one can travel on local buses which ply predetermined routes or charter/hire taxis to take one to his preferred destination.
By bus
To travel by road to Kumasi from Accra you will need to allow 6 hours travel time. Bus service is available by O.A. and STC, two private bus lines $12 for bus with AC.
By plane
Flights from Accra to Kumasi are in the morning and afternoon on the three carriers: Fly540Africa, CitiLink and Antrak. The flight is about 45 minutes long, limited on luggage allowance. Excellent way to get to Kumasi, preferred by most. Small planes, yet short trip. The cost on CitiLink is +-$90 USD one way, and $95 on Antrak as of June 2011 and $86 with Fly540Africa as of March 2012.
From may 2012 star bow airlines are flying this and other routes from Accra. Morning and afternoon flights, 100 seated planes and standard 20kg luggage, costs vary but typically around $60.
By car
Car rental in Kumasi is available at the lowest cost of about USD $75-100 per day.